Biopolymers
Quraxia is a leading Contract Research Organization (CRO) specializing in the synthesis and characterization of PLGA.
PLGA is a synthetic, biodegradable copolymer composed of two monomeric units: lactic acid (α-hydroxy propanoic acid) and glycolic acid (hydroxy acetic acid). It is synthesized in three forms: PLGA 50:50, 75:25, and 80:20.
PLGA represents a cornerstone technology in modern pharmaceutical and biomedical applications, offering unprecedented control over drug delivery while maintaining excellent biocompatibility.
Application:
Drug Delivery System:
Controlled release formulations: Microspheres, nanoparticles, and implants for sustained drug release
Parenteral depot formulations: Long-acting injectable reducing dosing frequency
Targeted delivery: Site-specific drug delivery minimizing systemic side effects
Therapeutic Applications
Oncology: Delivery of anticancer agents
Hormonal therapies: Treatment of cancer, endometriosis, and growth hormone deficiency
Vaccines: Long-acting vaccine delivery systems and immunotherapy applications
Neurological disorders: Delivery systems for treating Alzheimer's disease and stroke
Regenerative medicine: Scaffolds for tissue engineering and wound healing
Medical Devices
Surgical sutures: Biodegradable sutures
Orthopedic fixation devices: Temporary structural support that degrades over time
Ocular and dental applications: Localized treatment delivery
Quraxia is a leading Contract Research Organization (CRO) specializing in the synthesis and characterization of PLA.
PLA is a synthetic, biodegradable thermoplastic polyester.
PLA has been proven biocompatible through decades of clinical use in medical applications. The polymer is non-toxic and non-carcinogenic, making it suitable for direct contact with biological tissues and systems. PLA has received FDA approval for medical device applications and is classified as Generally Recognized as Safe (GRAS) for food contact application.
Applications in Medical and Pharmaceutical:
Drug delivery systems: PLA nanoparticles for controlled release of therapeutics, particularly in oncology and osteoarthritis treatment
Surgical applications: Biodegradable sutures, screws, pins, and fixation devices for orthopedic and dental procedures.
Tissue engineering: Scaffolds for bone, cartilage, and cardiovascular tissue regeneration
Implantable devices: Temporary implants that biodegrade over time, eliminating removal procedures
Advantage:
Medical grade biocompatible
Clinically safe
Non-toxic degradation products
Complete biodegradable
Environmental safe
No harmful emission
Incineration safe
Quraxia is a leading Contract Research Organization (CRO) specializing in the synthesis and characterization of PGA.
PGA is a synthetic, biodegradable thermoplastic polymer.
PGA represents a pioneering biodegradable polymer that has established the foundation for modern biodegradable materials in medical applications. Its combination of excellent mechanical properties, predictable biodegradation, and proven clinical safety makes it an invaluable material for surgical and therapeutic applications.
Applications:
Absorbable Surgical Sutures:
Surgical Reinforcement Materials
Tissue Engineering Scaffolds
Drug Delivery Systems
Advantage:
Exceptional Mechanical Properties
Superior Barrier Properties
Thermal Stability
Maintains structural integrity under thermal stress
Biocompatibility and Safety
Non-toxic degradation
Minimal tissue reaction
